If you’ve ever washed clothes thoroughly — collar, cuffs, the works — and still noticed a persistent greasy, musty smell once they’re dry, you’ve likely encountered nonenal. This stubborn compound is the real reason behind what many people call “old person smell,” and it doesn’t respond to regular laundry routines the way typical sweat odor does. The good news is that once you understand what nonenal is and why it clings to fabric, getting rid of it becomes much more straightforward.
This guide walks you through exactly how to remove nonenal odor from clothes using proven, practical methods — from everyday household ingredients to specialized products — so your wardrobe stays genuinely fresh.
What Is Nonenal and Why Does It Smell?
Nonenal, or 2-nonenal, is a chemical compound produced naturally by the human body. As we age — often starting around age 40 — the skin’s antioxidant defenses gradually decline. This causes unsaturated fatty acids on the skin’s surface to oxidize, producing nonenal as a byproduct. The result is that distinctive greasy, grassy odor often described as musty or stale.
What makes nonenal uniquely difficult to remove from clothing is its chemistry. It is hydrophobic (repels water) and oily in nature, meaning it doesn’t simply rinse away. It bonds to fabric fibers — particularly natural ones like cotton and linen — and resists the standard detergents most people use for laundry. Regular soap targets dirt and water-soluble sweat, but it does almost nothing against an oil-based compound like nonenal.
This is why clothes can come out of the washing machine smelling clean but start giving off that familiar musty scent again as soon as they warm up against the body.
Why Regular Washing Doesn’t Work
Understanding this helps explain the frustration many people and caregivers experience. Standard laundry detergents are formulated to tackle everyday soils and odors. They aren’t engineered to break down the waxy, fatty residue that nonenal leaves behind in fabric fibers.
Hot water alone isn’t enough, either — though it helps more than cold water. Without the right enzyme action or odor-neutralizing agents, nonenal compounds survive the wash cycle, dry back into the fabric, and re-activate with body heat.
The solution lies in choosing the right laundry additives and washing strategy specifically designed to cut through oily, oxidative residue.
How to Remove Nonenal Odor from Clothes: Step-by-Step
Step 1: Pre-Treat Problem Areas Before Washing
Nonenal concentrates in areas where skin makes the most contact with fabric — shirt collars, cuffs, underarms, the back of tops, and pillowcase edges. Before tossing the garment in the machine, pre-treat these zones.
- Spray with a dedicated odor-eliminating laundry spray
- Apply a small amount of enzyme-based stain remover and rub it in gently
- Or dab with a diluted white vinegar solution (equal parts vinegar and water)
Let the pre-treatment sit for 5–10 minutes before washing.
Step 2: Wash with Hot Water (Where the Fabric Allows)
Nonenal is oily, and oils respond to heat. Washing in the hottest water the garment’s care label permits helps dissolve the fatty residue more effectively, and allows any added detergent or washing booster to penetrate the fibers more deeply. For heat-sensitive fabrics, use warm water as a compromise.
Step 3: Add a Laundry Booster to Your Wash
This is the most critical step. One of the following boosters added to your regular wash cycle will significantly improve your results:
- White vinegar — Add one cup to the rinse cycle. Vinegar is mildly acidic and breaks down the oily compounds that create the odor without leaving a vinegar scent on the fabric once dried.
- Baking soda — Add half a cup with your detergent. It neutralizes odor at a molecular level and helps lift residue from fabric fibers.
- Borax — A natural mineral booster that enhances detergent performance and tackles stubborn, deep-set odors in heavily used garments like bedding and sleepwear.
- Enzyme-based detergent or additive — Products like enzyme-boosted detergents digest the organic compounds in nonenal. Look for formulas that specifically mention odor elimination, not just stain removal.
Step 4: Choose the Right Detergent
For nonenal odor, standard detergents fall short. Upgrade to one of the following:
- Enzyme-based laundry detergents (look for lipase enzymes, which specifically target fatty acids)
- Persimmon-based laundry products — Japanese persimmon (kaki) extract has a well-documented ability to neutralize nonenal. It’s the active ingredient in specialized products like Mirai Clinical’s laundry line.
- Activated charcoal-based detergents — Charcoal naturally adsorbs odor molecules, binding them so they rinse away with the water.
Step 5: Air Dry in Direct Sunlight When Possible
Skip the tumble dryer when you can. Hanging clothes outside in direct sunlight has two powerful benefits:
- UV radiation from sunlight breaks down residual nonenal compounds and kills odor-causing bacteria that survive the wash cycle.
- Fresh air circulation prevents moisture from being trapped in the fabric, which can reactivate musty odors in the dryer.
Even a few hours in the sun can make a noticeable difference — turn delicate items inside out to protect colors while still benefiting from UV exposure.
Step 6: Repeat If Needed for Stubborn or Set-In Odors
For garments that have retained nonenal odor over many washes, one treatment cycle may not be enough. Repeat the pre-treatment and boosted wash two or three times before concluding the odor is permanent. For very set-in cases, soaking the garment overnight in a diluted solution of white vinegar and warm water before a full wash can help loosen deep-seated residue.
Quick Comparison: Best Methods for Removing Nonenal Odor from Clothes
| Method | How It Works | Best Used For | Effort Level |
| White Vinegar (rinse cycle) | Breaks down oily residue; neutralizes odor compounds | Most fabric types | Low |
| Baking Soda (with detergent) | Neutralizes odor molecules; lifts fatty residue | Everyday clothes, bedding | Low |
| Enzyme-Based Detergent | Digests fatty acid compounds at molecular level | All garments, especially heavily worn | Medium |
| Persimmon-Based Products | Targets nonenal directly at the chemical level | Clothes and body hygiene combined | Medium |
| Borax (wash booster) | Enhances detergent; eliminates deep-set odors | Towels, bed linen, sleepwear | Low |
| Sunlight Air Drying | UV destroys bacteria and residual odor compounds | Any washable fabric | Low |
Fabrics Most Affected by Nonenal Odor
Not all materials hold on to nonenal equally. Understanding which fabrics are more susceptible helps you prioritize your laundry routine.
- Cotton — Highly absorbent, natural fiber that traps oily compounds easily. Requires consistent treatment.
- Linen — Similar to cotton; the porous weave holds nonenal but also releases it well with proper washing.
- Synthetic fabrics (polyester, nylon) — Can trap odors within the fiber structure and are often harder to fully deodorize. Enzyme-based detergents work best here.
- Wool — Naturally odor-resistant to a degree, but once nonenal sets in, it requires gentle specialized washing.
Switching to natural fiber clothing where possible also helps reduce odor retention over time, as natural fabrics breathe better and allow less buildup of the oily residue nonenal leaves behind.
Also Read This: How to Get Toothpaste Out of Clothes?
Addressing the Source: Preventing Nonenal from Transferring to Clothes
The most effective long-term strategy is reducing nonenal buildup on the skin before it ever reaches your clothing.
- Shower daily using a soap specifically formulated for nonenal — look for persimmon extract or tea tree-based body washes, which break down the fatty acid oxidation products on the skin’s surface.
- Exfoliate regularly with a loofah or washcloth to remove dead skin cells where nonenal tends to concentrate, particularly in skin folds and high-sweat zones.
- Change clothes daily — wearing garments more than once allows nonenal to accumulate in the fabric between washes.
- Eat antioxidant-rich foods — green tea, leafy vegetables, and citrus fruits help the body combat oxidative stress, which is the underlying mechanism that produces nonenal. A diet high in processed foods and saturated fats may increase nonenal production.
- Stay well hydrated — proper hydration supports skin turnover and helps flush compounds that contribute to aging-related body odor.
FAQ’s
What is nonenal odor?
Nonenal is a greasy, musty-smelling compound produced when fatty acids on aging skin oxidize. It is the primary cause of what’s commonly called “old person smell.”
Why won’t regular laundry detergent remove nonenal smell?
Because nonenal is oil-based and hydrophobic, standard detergents — which target water-soluble soils — can’t break it down effectively without enzyme boosters or acidic additives like vinegar.
Does white vinegar really remove nonenal from clothes?
Yes — adding one cup of white vinegar to the rinse cycle helps neutralize oily odor compounds. It won’t make clothes smell like vinegar; the scent dissipates completely as the fabric dries.
What is the best laundry product for nonenal odor?
Enzyme-based detergents combined with persimmon-based laundry additives deliver the strongest results, as they target nonenal’s fatty acid compounds directly at the molecular level.
At what age does nonenal odor start?
Nonenal production can begin as early as age 40, as the body’s antioxidant activity decreases and fatty acid oxidation on the skin increases. It becomes more noticeable after age 50.
Can nonenal smell be permanently removed from clothes?
In most cases, yes — with repeated treatment using enzyme detergents, vinegar, or persimmon-based products. For very old, set-in odor, an overnight vinegar soak before washing often works well.
Does sunlight help remove nonenal from fabric?
Yes. UV rays from natural sunlight break down residual nonenal compounds and kill odor-causing bacteria, making sun-drying significantly more effective than machine drying for these garments.
Is nonenal odor a sign of poor hygiene?
No. Nonenal is a natural byproduct of aging chemistry in the body. Even people with excellent hygiene routines can experience it because regular soap and water alone aren’t enough to neutralize this specific compound.
Conclusion
Removing nonenal odor from clothes requires a different approach than treating typical laundry smells. Because nonenal is oily, waxy, and water-resistant, success depends on using enzyme-based detergents, acidic rinse agents like white vinegar, or persimmon-based laundry products — combined with hot water washing and sun-drying wherever possible. Pre-treating collars, cuffs, and underarms before each wash makes a significant difference, especially for garments worn close to the skin.
Addressing the source by maintaining good skin hygiene with nonenal-targeting soaps and a diet rich in antioxidants will reduce how much of the compound transfers to clothing in the first place. With the right routine, nonenal odor is completely manageable — and your clothes can smell genuinely fresh again.

Shoaib is the creative mind behind FashionFreaking.com, sharing trendy insights on shoes, jewelry, clothes, and modern fashion to inspire confidence, style, and everyday elegance for fashion lovers worldwide.